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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX38 All Species: 17.88
Human Site: S199 Identified Species: 30.26
UniProt: Q92620 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92620 NP_054722.2 1227 140503 S199 S R R N E P E S P R H R P K D
Chimpanzee Pan troglodytes Q7YR39 1044 119631 K121 A G S S L Q K K R K K R K H L
Rhesus Macaque Macaca mulatta XP_001097681 1323 150587 S295 S R R N E P E S P R H R P K D
Dog Lupus familis XP_536800 1226 140550 S198 S R R N E P E S P R H R P K D
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 K243 T R E R T K G K S R Y R S R S
Rat Rattus norvegicus Q5XI69 779 88496
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025753 1230 141019 S198 S R R S E P E S P K H R P K D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957170 1258 143711 S222 T R R E E P E S P R N K P K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572947 1222 139562 D201 W D R D R G R D R D R D R S M
Honey Bee Apis mellifera XP_001122500 1093 125136 D170 T S R S N W D D D E D E E P R
Nematode Worm Caenorhab. elegans P34498 1131 129405 R186 W R S E R R N R D D E K R R R
Sea Urchin Strong. purpuratus XP_786478 1200 137247 R196 R R G R D S E R G N R S Q R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 V216 N E P E L Y Q V Y K G R V T R
Baker's Yeast Sacchar. cerevisiae P15938 1071 121634 Q148 D P S P N S E Q Q T Q N G H A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37 92.2 97.7 N.A. 37.7 22.6 N.A. N.A. 89.8 N.A. 81.3 N.A. 62.3 58.1 55.5 68.4
Protein Similarity: 100 53.7 92.6 99.1 N.A. 55.7 37.3 N.A. N.A. 95.1 N.A. 89.9 N.A. 77.3 72.1 71.3 81
P-Site Identity: 100 6.6 100 100 N.A. 20 0 N.A. N.A. 86.6 N.A. 73.3 N.A. 6.6 6.6 6.6 13.3
P-Site Similarity: 100 33.3 100 100 N.A. 40 0 N.A. N.A. 100 N.A. 93.3 N.A. 13.3 26.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 36.1 36.8 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 55 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 8 0 8 15 15 15 8 8 0 0 36 % D
% Glu: 0 8 8 22 36 0 50 0 0 8 8 8 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 0 0 8 8 0 8 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 29 0 0 15 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 8 15 0 22 8 15 8 36 0 % K
% Leu: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 0 0 22 15 0 8 0 0 8 8 8 0 0 0 % N
% Pro: 0 8 8 8 0 36 0 0 36 0 0 0 36 8 0 % P
% Gln: 0 0 0 0 0 8 8 8 8 0 8 0 8 0 0 % Q
% Arg: 8 58 50 15 15 8 8 15 15 36 15 50 15 22 22 % R
% Ser: 29 8 22 22 0 15 0 36 8 0 0 8 8 8 15 % S
% Thr: 22 0 0 0 8 0 0 0 0 8 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % V
% Trp: 15 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _